The Columbia CTNCC invites input from the public, community clinicians, and other stakeholders regarding novel treatment approaches that our CTN investigators should review and consider.

If you have a recommendation for a clinical treatment that you would like CTN researchers to consider for design into a future pilot study, please complete the “Treatment Research Ideas” form. Your idea may lead to a groundbreaking research project in the field of Lyme and the Tick-borne diseases.

The CTN will solicit suggestions from the public twice a year. A progress report for the previous round is now available.

The deadline for the second round of submissions for treatment research ideas from the general public is January 15, 2022.


Thanks to everyone who participated in our summer request for suggestions on treatment for TBD!

We received 104 suggestions. The suggestions varied widely. Some contributors recommended more than one approach to treatment. Your suggestions were not limited to treatment ideas: almost 30% described a diagnostic tool that could be used in TBD research. Many suggestions described intriguing cases and patient histories. Treatment research ideas described antibiotics, non-pharmacological types of treatment, and herbal treatment including diets and nutrition suggestions.

Your input is an invaluable way for our CTN Coordinating Center team to learn about novel treatment approaches that may improve the care of individuals with Lyme and other Tick-borne diseases.


In recognition of a severe unmet need, the Steven & Alexandra Cohen Foundation’s grant to Columbia University established the first national Columbia Clinical Trials Network Coordinating Center (CTNCC) for Lyme and Other Tick-borne Diseases. Under the leadership of Dr. Brian Fallon, this Clinical Trials Coordinating Center aims to propel national research toward the goal of identifying more effective treatments for patients with Lyme and other tick-borne diseases.

Providing oversight to ensure that the highest-quality clinical trials are undertaken, the CTN Coordinating Center at Columbia will provide funding support for small pilot studies, assist investigators in protocol design and statistical research planning, establish and manage a national case registry, and create a data management system for multi-site clinical trials. The clinical trials network will be a powerful engine to drive large-scale clinical trials and potentially transformational early-stage research.